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Delta-8 THC is a naturally occurring cannabinoid and analog of tetrahydrocannabinol (THC). It can be isolated as a minor cannabinoid from the cannabis plant. Compared to delta-9 THC, it is more pharmacologically active with increased duration and decreased intensity of effects. Delta-8 THC has few or no traits that aid in its identification or distinction from other cannabinoids such as CBD or CBN.

Delta-8 THC was first described by American chemist Raphael Mechoulam at Hebrew University Medical School, Jerusalem in 1965. In 2010, Dr Yann le Menachof at INSERM found delta-8 THC may help damage brain tumors due to its ability to selectively kill glioma cells.

Delta-8 THC has both low toxicity and minimal psychoactive effects making it of significant interest for therapeutic use. Delta-8 THC induces the secretion of Calcitonin gene related peptide (CGRP), which acts as an anti inflammatory agent. It also inhibits the release of substance P, which is responsible for pain transmission in neurons. This means that delta-8 THC can act to reduce inflammation and block nerve signals to prevent any excruciating pain felt by patients during chemotherapy treatment. Click reference here Due to its high affinity with cannabinoid receptors, delta-8 THC may provide relief from anxiety disorders such as social phobias or PTSD without causing the disorientating psychological side effects associated with many cannabinoids including THC.

Delta-8 THC is non-psychoactive because it is not well absorbed in the brain, and when taken orally does not reach the blood–brain barrier. In comparison to delta-9 THC, which produces a stronger high but causes severe mood alterations due to its ability to cross the blood-brain barrier, delta-8 THC provides medical patients with the same therapeutic benefits of cannabis without causing unpleasant or harmful side effects.

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